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CAS 68 19 9 Herbal Plant Extract Vitamin B12 Cyanocobalamin Cobalamin For Dementia / Cognitive Function

CAS 68 19 9 Herbal Plant Extract Vitamin B12 Cyanocobalamin Cobalamin For Dementia / Cognitive Function

  • CAS 68 19 9 Herbal Plant Extract Vitamin B12 Cyanocobalamin Cobalamin For Dementia / Cognitive Function
CAS 68 19 9 Herbal Plant Extract Vitamin B12 Cyanocobalamin Cobalamin For Dementia / Cognitive Function
Product Details:
Place of Origin: China
Brand Name: Phytocare
Payment & Shipping Terms:
Minimum Order Quantity: Negotiation
Price: Negotiation
Packaging Details: 100g/tin, 1kg/tin, 25kg/drum
Payment Terms: L/C, D/A, D/P, T/T,PAYPAL
Supply Ability: 2000kg/month
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Detailed Product Description
Product: Vitamin B12 Other Name: Cyanocobalamin (Cobalamin)
CAS No.: 68-19-9 Purity: 97.0-102.0%
Appearance: Dark Red Crystals Or Dark Red Crystalline Functions: Dementia And Cognitive Function, Cardiovascular Diseases
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Natural Dietary Supplements VitaminB12 (Cyanocobalamin) (Cobalamin) for Dementia and cognitive function


Vitamin B12 is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and a prescription medication. Vitamin B12 exists in several forms and contains the mineral cobalt, so compounds with vitamin B12 activity are collectively called “cobalamins”. Methylcobalamin and 5-deoxyadenosylcobalamin are the forms of vitamin B12 that are active in human metabolism.

 

Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis. Vitamin B12 functions as a cofactor for methionine synthase and L-methylmalonyl-CoA mutase. Methionine synthase catalyzes the conversion of homocysteine to methionine. Methionine is required for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 different substrates, including DNA, RNA, hormones, proteins, and lipids. L-methylmalonyl-CoA mutase converts L-methylmalonyl-CoA to succinyl-CoA in the degradation of propionate an essential biochemical reaction in fat and protein metabolism. Succinyl-CoA is also required for hemoglobin synthesis.

 

Vitamin B12, bound to protein in food, is released by the activity of hydrochloric acid and gastric protease in the stomach. When synthetic vitamin B12 is added to fortified foods and dietary supplements, it is already in free form and, thus, does not require this separation step. Free vitamin B12 then combines with intrinsic factor, a glycoprotein secreted by the stomach’s parietal cells, and the resulting complex undergoes absorption within the distal ileum by receptor-mediated endocytosis. Approximately 56% of a 1 mcg oral dose of vitamin B12 is absorbed, but absorption decreases drastically when the capacity of intrinsic factor is exceeded (at 1–2 mcg of vitamin B12).

 

Benefits & Applications:

Pharmaceuticals

Dietary Supplements

Treatment of Cardiovascular diseases

Dementia and cognitive function

 

Certificate of Analysis:

 

Product Name: Cyanocobalamin (Vitamin B12)                                                   Batch No.: C180707

MFG: July 08, 2018                                                                                     Expiry Date: July 07, 2023

Report on: July 19, 2018                                                                                              Quantity: 100kg

Items Standards Test Result
Characters Dark red crystals or dark red crystalline Complies
Identification A UV: Absorption maxima at 278±1nm,361±1nm and 550±2nm Complies
 

A361nm/A278nm: 1.70-1.90

A361nm/A550nm: 3.15-3.45

1.85

3.27

Identification B TLC: The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution Complies
Loss on drying ≤10.0% 3.7%
Assay 97.0%-102.0% 98.9%
Related substances Total impurities ≤3.0% 0.7%
Acetone ≤5000 ppm Not detected
The total aerobic microbial count ≤1000 cfu/g <10 cfu/g
The total combines yeasts/mold count ≤100 cfu/g <10 cfu/g
Purity (HPLC) ≥98.0% 98.5%
Conclusion

QUALIFIED

Complies with the specification of EP9.0, BP2018

 

 

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